Drug profile

The FDA adverse-event record for Vinblastine

28 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Vinblastine. See the species affected, top reactions, and outcomes below.

28
adverse-event reports
21.4%
death-coded share
Dog
most-reported species
5
Diarrhoea - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
28
Total Reports
6
Deaths Reported
21.4%
Death Rate

Active Ingredients

Vinblastine

Administration Routes

UnknownIntravenous

Species Affected

Dog 25
Cat 3

Most Affected Breeds

Retriever - Labrador 6
Pug 3
Domestic Shorthair 3
Shih Tzu 3
Retriever - Golden 3
Bulldog - French 2
Mixed (Dog) 2
Terrier - Boston 1
Shar Pei 1
Bichon Frise 1

Most Reported Reactions

Diarrhoea 5
Elevated serum alkaline phosphatase (SAP) 5
Lethargy (see also Central nervous system depression in 'Neurological') 5
Elevated alanine aminotransferase (ALT) 4
Vomiting 4
Decreased appetite 4
Death by euthanasia 4
Emesis 3
Elevated liver enzymes 3
Other abnormal test result NOS 3
Thrombocytopenia 3
Anaemia NOS 3

Outcome Breakdown

Ongoing
17 (58.6%)
Euthanized
5 (17.2%)
Recovered/Normal
4 (13.8%)
Died
2 (6.9%)
Outcome Unknown
1 (3.4%)

Vinblastine Adverse Event Insights

28 reports name Vinblastine; 6 recorded a death outcome (21.4% of reported events, not a population-level mortality rate). Active ingredient: Vinblastine. Administration routes: Unknown, Intravenous.

By species: Dog (25 reports), Cat (3 reports). By breed: Retriever - Labrador (6), Pug (3), Domestic Shorthair (3).

Leading clinical signs: Diarrhoea (5), Elevated serum alkaline phosphatase (SAP) (5), Lethargy (see also Central nervous system depression in 'Neurological') (5), Elevated alanine aminotransferase (ALT) (4). Outcome, 29 coded reports: Ongoing leads at 58.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.