Verdinexor

579 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

579

Total Reports

225

Deaths Reported

3890.0%

Death Rate

Active Ingredients

Verdinexor

Administration Routes

OralUnknownTopical

Species Affected

Dog 576

Human 3

Most Affected Breeds

Retriever - Labrador 77

Retriever - Golden 48

Dog (unknown) 41

American Pit Bull Terrier 40

Beagle 26

Crossbred Canine/dog 22

Collie - Border 17

Shih Tzu 16

Boxer (German Boxer) 15

Shepherd Dog - German 13

Most Reported Reactions

Vomiting 162

Death by euthanasia 161

Weight loss 146

Diarrhoea 108

Lack of efficacy - NOS 98

Decreased appetite 93

Elevated alanine aminotransferase (ALT) 91

Thrombocytopenia 77

Anorexia 70

Elevated serum alkaline phosphatase (SAP) 67

Lethargy (see also Central nervous system depression in 'Neurological') 61

Death 59

Outcome Breakdown

Outcome Unknown

225 (38.9%)

Euthanized

163 (28.2%)

Ongoing

72 (12.4%)

Died

62 (10.7%)

Recovered/Normal

55 (9.5%)

Recovered with Sequela

2 (0.3%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.