Drug profile

The FDA adverse-event record for Unspecified Thyroid Medication

80 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Unspecified Thyroid Medication. See the species affected, top reactions, and outcomes below.

80
adverse-event reports
18.8%
death-coded share
Dog
most-reported species
19
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
80
Total Reports
15
Deaths Reported
18.8%
Death Rate

Active Ingredients

Unspecified Thyroid Medication

Administration Routes

OralUnknownTopicalOther

Species Affected

Dog 58
Cat 21
Human 1

Most Affected Breeds

Retriever - Labrador 13
Domestic Shorthair 12
Chihuahua 2
Shepherd Dog - German 2
Terrier - Boston 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Siamese 2
Domestic Longhair 2
Beagle 2
Siberian Husky 2

Most Reported Reactions

Vomiting 19
Not eating 12
Lethargy (see also Central nervous system depression in Neurological) 12
Diarrhoea 11
Weight loss 10
Death by euthanasia 10
Anorexia 9
Lethargy (see also Central nervous system depression in 'Neurological') 7
Death 5
Seizure NOS 5
Behavioural disorder NOS 5
Lack of efficacy - NOS 5

Outcome Breakdown

Outcome Unknown
26 (32.5%)
Recovered/Normal
20 (25.0%)
Ongoing
18 (22.5%)
Euthanized
10 (12.5%)
Died
5 (6.3%)
Recovered with Sequela
1 (1.3%)

Unspecified Thyroid Medication Adverse Event Insights

80 reports name Unspecified Thyroid Medication; 15 recorded a death outcome (18.8% of reported events, not a population-level mortality rate). Active ingredient: Unspecified Thyroid Medication. Administration routes: Oral, Unknown, Topical, Other.

By species: Dog (58 reports), Cat (21 reports), Human (1 reports). By breed: Retriever - Labrador (13), Domestic Shorthair (12), Chihuahua (2).

Leading clinical signs: Vomiting (19), Not eating (12), Lethargy (see also Central nervous system depression in Neurological) (12), Diarrhoea (11). Outcome, 80 coded reports: Outcome Unknown leads at 32.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.