Unspecified Thyroid Medication

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80 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
80
Total Reports
15
Deaths Reported
1880.0%
Death Rate

Active Ingredients

Unspecified Thyroid Medication

Administration Routes

OralUnknownTopicalOther

Species Affected

Dog 58
Cat 21
Human 1

Most Affected Breeds

Retriever - Labrador 13
Domestic Shorthair 12
Chihuahua 2
Shepherd Dog - German 2
Terrier - Boston 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Siamese 2
Domestic Longhair 2
Beagle 2
Siberian Husky 2

Most Reported Reactions

Vomiting 19
Not eating 12
Lethargy (see also Central nervous system depression in Neurological) 12
Diarrhoea 11
Weight loss 10
Death by euthanasia 10
Anorexia 9
Lethargy (see also Central nervous system depression in 'Neurological') 7
Death 5
Seizure NOS 5
Behavioural disorder NOS 5
Lack of efficacy - NOS 5

Outcome Breakdown

Outcome Unknown
26 (32.5%)
Recovered/Normal
20 (25.0%)
Ongoing
18 (22.5%)
Euthanized
10 (12.5%)
Died
5 (6.3%)
Recovered with Sequela
1 (1.3%)

Data Summary

Metric Value
Total adverse event reports 80
Reports involving death 15
Case-fatality rate (reported events) 1880.0%
Distinct species in reports 3
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Unspecified Thyroid Medication Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 80 adverse event reports referencing Unspecified Thyroid Medication, including 15 reports in which the animal died — a 1880.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Unspecified Thyroid Medication. Reported administration routes include Oral, Unknown, Topical, Other. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Unspecified Thyroid Medication reports are Dog (58 reports), Cat (21 reports), Human (1 reports), with Dog accounting for the largest share. Within those species, Retriever - Labrador (13), Domestic Shorthair (12), Chihuahua (2) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Unspecified Thyroid Medication are Vomiting (19), Not eating (12), Lethargy (see also Central nervous system depression in Neurological) (12), Diarrhoea (11). Of the 80 reports with a coded outcome, Outcome Unknown is the leading category at 32.5%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Unspecified Thyroid Medication.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial