Drug profile

The FDA adverse-event record for Unspecified Thyroid Medication

80 FDA reports name Unspecified Thyroid Medication, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#875 of 2,679
by report volume (all drugs)
80
adverse-event reports
18.8%
death-coded share
Dog
most-reported species
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Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Unspecified Thyroid Medication ranks #871 of 2679 by total reports (80) and #263 of 1130 by death-coded share (18.8%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#871
This drug, reports of 2679
#263
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Unspecified Thyroid Medication has 80 reports now versus 80 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Unspecified Thyroid Medication changes

Signature read: death-coded report count at 15 is the most distinctive stamp on Unspecified Thyroid Medication's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
80
Total Reports
15
Deaths Reported
18.8%
Death-coded share of reports

Active Ingredients

Unspecified Thyroid Medication

Administration Routes

OralUnknownTopicalOther

Species Affected

Dog 58
Cat 21
Human 1

Most Affected Breeds

Retriever - Labrador 13
Domestic Shorthair 12
Chihuahua 2
Shepherd Dog - German 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Terrier - Boston 2
Siamese 2
Domestic Longhair 2
Beagle 2
Siberian Husky 2

Most Reported Reactions

Vomiting 19
Not eating 12
Lethargy (see also Central nervous system depression in Neurological) 12
Diarrhoea 11
Weight loss 10
Death by euthanasia 10
Anorexia 9
Lethargy (see also Central nervous system depression in 'Neurological') 7
Death 5
Seizure NOS 5
Behavioural disorder NOS 5
Lack of efficacy - NOS 5

Outcome Breakdown

Outcome Unknown
26 (32.5%)
Recovered/Normal
20 (25.0%)
Ongoing
18 (22.5%)
Euthanized
10 (12.5%)
Died
5 (6.3%)
Recovered with Sequela
1 (1.3%)

Unspecified Thyroid Medication: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Unspecified Thyroid Medication, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (18.8% here), distinct from the volume row.

Enrofloxacin 18.7% Feline Calicivirus, Strain F-9, Passage 7, Lot A; Feline Chlamydia Psittaci, Str 18.8% Prebiotics, Microorganisms 18.8% Lysine 18.7%

What to do with this drug

  • Compare Unspecified Thyroid Medication's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Unspecified Thyroid Medication (#875 of 2,679 by report volume); death-coded 18.8%. PlainBreed drug row · death-coded report count stamp 15 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →