Drug profile

The FDA adverse-event record for Unspecified Imidacloprid

11 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Unspecified Imidacloprid. See the species affected, top reactions, and outcomes below.

11
adverse-event reports
9.1%
death-coded share
Cat
most-reported species
7
Lack of efficacy (ectoparasite) - flea - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
11
Total Reports
1
Deaths Reported
9.1%
Death Rate

Active Ingredients

Unspecified Imidacloprid

Administration Routes

TopicalUnknown

Species Affected

Cat 8
Dog 3

Most Affected Breeds

Domestic Shorthair 3
Domestic Mediumhair 1
Siamese 1
Maine Coon 1
Bulldog - French 1
Pug 1
Domestic Longhair 1
Mixed (Cat) 1
Dog (unknown) 1

Most Reported Reactions

Lack of efficacy (ectoparasite) - flea 7
Hyperactivity 2
Scratching 2
Behavioural disorder NOS 2
Excessive chewing, licking and/or grooming 1
Not eating 1
Vocalisation 1
Lethargy (see also Central nervous system depression in 'Neurological') 1
Hypothermia 1
Decreased packed cell volume (PCV) 1
Leucocytosis NOS 1
Other blood disorder NOS 1

Outcome Breakdown

Outcome Unknown
10 (90.9%)
Euthanized
1 (9.1%)

Unspecified Imidacloprid Adverse Event Insights

11 reports name Unspecified Imidacloprid; 1 recorded a death outcome (9.1% of reported events, not a population-level mortality rate). Active ingredient: Unspecified Imidacloprid. Administration routes: Topical, Unknown.

By species: Cat (8 reports), Dog (3 reports). By breed: Domestic Shorthair (3), Domestic Mediumhair (1), Siamese (1).

Leading clinical signs: Lack of efficacy (ectoparasite) - flea (7), Hyperactivity (2), Scratching (2), Behavioural disorder NOS (2). Outcome, 11 coded reports: Outcome Unknown leads at 90.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.