Drug profile

The FDA adverse-event record for Unspecified Heartworm Medication

16 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Unspecified Heartworm Medication. See the species affected, top reactions, and outcomes below.

16
adverse-event reports
31.3%
death-coded share
Dog
most-reported species
5
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
16
Total Reports
5
Deaths Reported
31.3%
Death Rate

Active Ingredients

Unspecified Heartworm Medication

Administration Routes

UnknownOral

Species Affected

Dog 16

Most Affected Breeds

Dog (unknown) 3
Hound (unspecified) 1
Terrier - Jack Russell 1
Weimaraner 1
Newfoundland 1
Unknown 1
Terrier - Yorkshire 1
Dachshund - Standard Long-haired 1
Pinscher - Miniature 1
Crossbred Canine/dog 1

Most Reported Reactions

Death 5
Not eating 4
Diarrhoea 3
Lethargy (see also Central nervous system depression in Neurological) 3
Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders') 2
Behavioural disorder NOS 2
Sleepiness - systemic disorder 2
Vomiting 2
Injection site pain 1
Injection site abscess 1
Loose stool 1
Flatulence, bloating and distension 1

Outcome Breakdown

Outcome Unknown
5 (31.3%)
Died
5 (31.3%)
Recovered/Normal
4 (25.0%)
Ongoing
2 (12.5%)

Unspecified Heartworm Medication Adverse Event Insights

16 reports name Unspecified Heartworm Medication; 5 recorded a death outcome (31.3% of reported events, not a population-level mortality rate). Active ingredient: Unspecified Heartworm Medication. Administration routes: Unknown, Oral.

By species: Dog (16 reports). By breed: Dog (unknown) (3), Hound (unspecified) (1), Terrier - Jack Russell (1).

Leading clinical signs: Death (5), Not eating (4), Diarrhoea (3), Lethargy (see also Central nervous system depression in Neurological) (3). Outcome, 16 coded reports: Outcome Unknown leads at 31.3%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.