Drug profile

The FDA adverse-event record for Unspecified Ear Flush

19 FDA reports name Unspecified Ear Flush, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#1882 of 2,679
by report volume (all drugs)
19
adverse-event reports
10.5%
death-coded share
Dog
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Unspecified Ear Flush ranks #1827 of 2679 by total reports (19). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1827
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Unspecified Ear Flush has 19 reports now versus 18 in that prior snapshot: 1 more (5.6%).

Report change
+1
Death-coded reports
+1
Death-coded share
+5.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Unspecified Ear Flush changes

Signature read: 19 reports place Unspecified Ear Flush in the lower third of FDA AER volume (#1882 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
19
Total Reports
2
Deaths Reported
10.5%
Death-coded share of reports

Active Ingredients

Unspecified Ear Flush

Administration Routes

Auricular (Otic)Unknown

Species Affected

Dog 16
Cat 3

Most Affected Breeds

Retriever - Golden 3
Boxer (German Boxer) 3
Domestic Shorthair 3
Chihuahua 2
Lhasa Apso 1
Terrier - Boston 1
Shepherd Dog - Belgian Malinois 1
Retriever - Labrador 1
Pug 1
Crossbred Canine/dog 1

Most Reported Reactions

Nystagmus 5
Hyperglycaemia 4
Ataxia 4
Glucosuria 3
Head tilt - neurological disorder (see also Head tilt - ear disorder) 3
Vocalisation 3
Deafness 2
Head tilt - ear disorder 2
Lack of efficacy - NOS 2
Elevated alanine aminotransferase (ALT) 2
Death by euthanasia 2
Hives (see also 'Skin') 2

Outcome Breakdown

Outcome Unknown
7 (36.8%)
Ongoing
6 (31.6%)
Recovered/Normal
3 (15.8%)
Euthanized
2 (10.5%)
Recovered with Sequela
1 (5.3%)

Unspecified Ear Flush: lower report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Unspecified Ear Flush (#1882 of 2,679 by report volume); death-coded 10.5%. PlainBreed drug row · report volume stamp 19 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →