Drug profile

The FDA adverse-event record for Unspecified Butorphanol

Name: Unspecified Butorphanol - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

11 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Unspecified Butorphanol. See the species affected, top reactions, and outcomes below.

11
adverse-event reports: 27.3%
death-coded share: Dog
most-reported species: 3
Unable to walk - top reaction

Compiled by PlainBreed Editorial, Pet Health Editorial Team

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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

27.3%

Death Rate

Active Ingredients

Unspecified Butorphanol

Administration Routes

IntravenousUnknownIntramuscular

Species Affected

Dog 8

Cat 3

Most Affected Breeds

Deutsche Dogge, Great Dane 3

Domestic Shorthair 2

Cat (other) 1

Retriever (unspecified) 1

Spitz - American Eskimo Dog 1

Siberian Husky 1

Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1

Bulldog - American 1

Most Reported Reactions

Unable to walk 3

Seizure NOS 2

Abnormal movement NOS 2

Depressed reflexes 2

Hyperactivity 2

Proprioception deficit 2

Urinary tract infection 2

Myelopathy NOS 2

Haematuria 2

Underdose 2

Panting 2

Lack of efficacy - NOS 1

Outcome Breakdown

Recovered/Normal

4 (36.4%)

Ongoing

3 (27.3%)

Euthanized

2 (18.2%)

Died

1 (9.1%)

Outcome Unknown

1 (9.1%)

Unspecified Butorphanol Adverse Event Insights

11 reports name Unspecified Butorphanol; 3 recorded a death outcome (27.3% of reported events, not a population-level mortality rate). Active ingredient: Unspecified Butorphanol. Administration routes: Intravenous, Unknown, Intramuscular.

By species: Dog (8 reports), Cat (3 reports). By breed: Deutsche Dogge, Great Dane (3), Domestic Shorthair (2), Cat (other) (1).

Leading clinical signs: Unable to walk (3), Seizure NOS (2), Abnormal movement NOS (2), Depressed reflexes (2). Outcome, 11 coded reports: Recovered/Normal leads at 36.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.