Drug profile

The FDA adverse-event record for Triple Antibiotic

31 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Triple Antibiotic. See the species affected, top reactions, and outcomes below.

31
adverse-event reports
6.5%
death-coded share
Dog
most-reported species
7
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
31
Total Reports
2
Deaths Reported
6.5%
Death Rate

Active Ingredients

Triple Antibiotic

Administration Routes

OphthalmicTopicalUnknown

Species Affected

Dog 22
Cat 9

Most Affected Breeds

Domestic Shorthair 7
Shih Tzu 3
Poodle - Toy 2
Pug 2
Maltese 2
Terrier - Airedale 1
Pinscher - Miniature 1
Spaniel - Springer English 1
Dachshund - Standard Long-haired 1
Boxer (German Boxer) 1

Most Reported Reactions

Vomiting 7
Lethargy (see also Central nervous system depression in 'Neurological') 7
Eye disorder NOS (for photophobia see 'neurological') 5
Elevated liver enzymes 5
Other abnormal test result NOS 5
Dehydration 5
Weakness 5
Emesis 5
Fever 4
Lack of efficacy - NOS 4
Nasal discharge 4
Anorexia 4

Outcome Breakdown

Ongoing
21 (67.7%)
Recovered/Normal
7 (22.6%)
Died
1 (3.2%)
Recovered with Sequela
1 (3.2%)
Euthanized
1 (3.2%)

Triple Antibiotic Adverse Event Insights

31 reports name Triple Antibiotic; 2 recorded a death outcome (6.5% of reported events, not a population-level mortality rate). Active ingredient: Triple Antibiotic. Administration routes: Ophthalmic, Topical, Unknown.

By species: Dog (22 reports), Cat (9 reports). By breed: Domestic Shorthair (7), Shih Tzu (3), Poodle - Toy (2).

Leading clinical signs: Vomiting (7), Lethargy (see also Central nervous system depression in 'Neurological') (7), Eye disorder NOS (for photophobia see 'neurological') (5), Elevated liver enzymes (5). Outcome, 31 coded reports: Ongoing leads at 67.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.