Drug profile

The FDA adverse-event record for Trimeprazine Tartrate + Prednisolone

28 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Trimeprazine Tartrate + Prednisolone. See the species affected, top reactions, and outcomes below.

28
adverse-event reports
10.7%
death-coded share
Dog
most-reported species
5
Lack of efficacy - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
28
Total Reports
3
Deaths Reported
10.7%
Death Rate

Active Ingredients

Trimeprazine Tartrate + Prednisolone

Administration Routes

UnknownOral

Species Affected

Dog 28

Most Affected Breeds

Retriever - Labrador 3
Poodle - Toy 2
Chihuahua 2
Terrier - Cairn 2
Crossbred Canine/dog 2
Dachshund (unspecified) 1
Terrier - Bull - American Pit 1
American Pit Bull Terrier 1
Terrier - West Highland White 1
Retriever - Golden 1

Most Reported Reactions

Lack of efficacy - NOS 5
Anorexia 4
Vomiting 3
Bruising 3
Decreased haematocrit 3
Leucocytosis NOS 3
Restlessness 2
Weight gain 2
Lack of efficacy (endoparasite) - heartworm 2
Allergy NOS 2
Perineal fistula 2
Falling 2

Outcome Breakdown

Outcome Unknown
15 (53.6%)
Ongoing
6 (21.4%)
Recovered/Normal
4 (14.3%)
Euthanized
2 (7.1%)
Died
1 (3.6%)

Trimeprazine Tartrate + Prednisolone Adverse Event Insights

28 reports name Trimeprazine Tartrate + Prednisolone; 3 recorded a death outcome (10.7% of reported events, not a population-level mortality rate). Active ingredient: Trimeprazine Tartrate + Prednisolone. Administration routes: Unknown, Oral.

By species: Dog (28 reports). By breed: Retriever - Labrador (3), Poodle - Toy (2), Chihuahua (2).

Leading clinical signs: Lack of efficacy - NOS (5), Anorexia (4), Vomiting (3), Bruising (3). Outcome, 28 coded reports: Outcome Unknown leads at 53.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.