Drug profile

The FDA adverse-event record for Triheart Plus

12 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Triheart Plus. See the species affected, top reactions, and outcomes below.

12
adverse-event reports
8.3%
death-coded share
Dog
most-reported species
4
Unable to walk - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
12
Total Reports
1
Deaths Reported
8.3%
Death Rate

Active Ingredients

Triheart Plus

Administration Routes

OralUnknown

Species Affected

Dog 12

Most Affected Breeds

Sheepdog - Old English (Bobtail) 3
Retriever - Labrador 1
Dachshund (unspecified) 1
Chihuahua 1
Bulldog 1
Shepherd Dog - Australian 1
Terrier - Bull - American Pit 1
Shih Tzu 1
Deutsche Dogge, Great Dane 1
Alaskan Malamute 1

Most Reported Reactions

Unable to walk 4
Vomiting 3
Walking difficulty 3
Limpness 3
Lack of efficacy (endoparasite) - heartworm 2
Seizure NOS 1
Tremor 1
Head tremor 1
INEFFECTIVE, ATOPY CONTROL 1
Tongue disorder NOS 1
Gall bladder & bile duct disorder NOS 1
Polydipsia 1

Outcome Breakdown

Ongoing
5 (41.7%)
Recovered/Normal
4 (33.3%)
Outcome Unknown
2 (16.7%)
Euthanized
1 (8.3%)

Triheart Plus Adverse Event Insights

12 reports name Triheart Plus; 1 recorded a death outcome (8.3% of reported events, not a population-level mortality rate). Active ingredient: Triheart Plus. Administration routes: Oral, Unknown.

By species: Dog (12 reports). By breed: Sheepdog - Old English (Bobtail) (3), Retriever - Labrador (1), Dachshund (unspecified) (1).

Leading clinical signs: Unable to walk (4), Vomiting (3), Walking difficulty (3), Limpness (3). Outcome, 12 coded reports: Ongoing leads at 41.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.