Drug profile

The FDA adverse-event record for Triheart

Name: Triheart - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

44 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Triheart. See the species affected, top reactions, and outcomes below.

44
adverse-event reports: 0.0%
death-coded share: Dog
most-reported species: 28
Lack of efficacy (endoparasite) - heartworm - top reaction

Compiled by PlainBreed Editorial, Pet Health Editorial Team

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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

0.0%

Death Rate

Active Ingredients

Triheart

Administration Routes

OralUnknown

Species Affected

Dog 44

Most Affected Breeds

Retriever - Labrador 10

Shepherd Dog - German 5

Terrier - Bull - American Pit 4

Crossbred Canine/dog 4

Chihuahua 3

Dog (unknown) 2

Collie - Border 1

Mixed (Dog) 1

Shepherd Dog - Belgian Malinois 1

Coonhound (unspecified) 1

Most Reported Reactions

Lack of efficacy (endoparasite) - heartworm 28

Diarrhoea 4

Seizure NOS 3

Vomiting 3

Tremor 2

Elevated aspartate aminotransferase (AST) 2

Elevated alanine aminotransferase (ALT) 2

Shaking 2

Not sleeping 2

Behavioural disorder NOS 1

Bloody diarrhoea 1

Weight loss 1

Outcome Breakdown

Ongoing

36 (81.8%)

Outcome Unknown

4 (9.1%)

Recovered/Normal

4 (9.1%)

Triheart Adverse Event Insights

44 reports name Triheart; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Triheart. Administration routes: Oral, Unknown.

By species: Dog (44 reports). By breed: Retriever - Labrador (10), Shepherd Dog - German (5), Terrier - Bull - American Pit (4).

Leading clinical signs: Lack of efficacy (endoparasite) - heartworm (28), Diarrhoea (4), Seizure NOS (3), Vomiting (3). Outcome, 44 coded reports: Ongoing leads at 81.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.