Drug profile

The FDA adverse-event record for Trenbolone; Estradiol; Tylosin Tartrate

85 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Trenbolone; Estradiol; Tylosin Tartrate. See the species affected, top reactions, and outcomes below.

85
adverse-event reports
62.4%
death-coded share
Cattle
most-reported species
46
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
85
Total Reports
53
Deaths Reported
62.4%
Death Rate

Active Ingredients

Trenbolone; Estradiol; Tylosin Tartrate

Administration Routes

OtherUnknownSubcutaneousParenteralCutaneous

Species Affected

Cattle 76
Unknown 9

Most Affected Breeds

Cattle (unknown) 27
Crossbred Bovine/Cattle 26
Holstein-Friesian also known as Holstein 15
Unknown 9
Cattle (other) 2
Charolais 2
Mixed (Cattle) 2
Maine-Anjou 1
Holstein-Friesian - French Black Pied 1

Most Reported Reactions

Death 46
Behavioural disorder NOS 28
Unclassifiable adverse event 27
Respiratory tract disorder NOS 25
Digestive tract disorder NOS 17
Pneumonia 17
Lameness 16
Weight gain 9
Peritonitis 8
Ruminal bloat 8
Musculoskeletal disorder NOS 6
Reticulitis 6

Outcome Breakdown

Outcome Unknown
56 (44.4%)
Died
51 (40.5%)
Euthanized
8 (6.3%)
Ongoing
7 (5.6%)
Recovered/Normal
4 (3.2%)

Trenbolone; Estradiol; Tylosin Tartrate Adverse Event Insights

85 reports name Trenbolone; Estradiol; Tylosin Tartrate; 53 recorded a death outcome (62.4% of reported events, not a population-level mortality rate). Active ingredient: Trenbolone; Estradiol; Tylosin Tartrate. Administration routes: Other, Unknown, Subcutaneous, Parenteral.

By species: Cattle (76 reports), Unknown (9 reports). By breed: Cattle (unknown) (27), Crossbred Bovine/Cattle (26), Holstein-Friesian also known as Holstein (15).

Leading clinical signs: Death (46), Behavioural disorder NOS (28), Unclassifiable adverse event (27), Respiratory tract disorder NOS (25). Outcome, 126 coded reports: Outcome Unknown leads at 44.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.