Drug profile

The FDA adverse-event record for Trenbolone Acetate & Estradiol

16 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Trenbolone Acetate & Estradiol. See the species affected, top reactions, and outcomes below.

16
adverse-event reports
62.5%
death-coded share
Cattle
most-reported species
6
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
16
Total Reports
10
Deaths Reported
62.5%
Death Rate

Active Ingredients

Trenbolone Acetate & Estradiol

Administration Routes

UnknownSubcutaneous

Species Affected

Cattle 16

Most Affected Breeds

Mixed (Cattle) 9
Cattle (other) 3
Crossbred Bovine/Cattle 3
Cattle (unknown) 1

Most Reported Reactions

Death 6
Lack of efficacy - NOS 5
Lack of efficacy (bacteria) - NOS 3
Anaphylactic-type reaction 3
Death by euthanasia 2
Lack of efficacy 2
PR-LUNG(S), LESION(S) 1
DEATH-TREATMENT FAILURE 1
CULTURE/TITER DATA ABNORMAL 1
Unrelated death 1
Abscess NOS 1
Weight loss 1

Outcome Breakdown

Died
8 (38.1%)
Outcome Unknown
6 (28.6%)
Recovered/Normal
3 (14.3%)
Euthanized
2 (9.5%)
Ongoing
1 (4.8%)
Recovered with Sequela
1 (4.8%)

Trenbolone Acetate & Estradiol Adverse Event Insights

16 reports name Trenbolone Acetate & Estradiol; 10 recorded a death outcome (62.5% of reported events, not a population-level mortality rate). Active ingredient: Trenbolone Acetate & Estradiol. Administration routes: Unknown, Subcutaneous.

By species: Cattle (16 reports). By breed: Mixed (Cattle) (9), Cattle (other) (3), Crossbred Bovine/Cattle (3).

Leading clinical signs: Death (6), Lack of efficacy - NOS (5), Lack of efficacy (bacteria) - NOS (3), Anaphylactic-type reaction (3). Outcome, 21 coded reports: Died leads at 38.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.