Drug profile

The FDA adverse-event record for Topical Skin Treatment (Unknown)

43 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Topical Skin Treatment (Unknown). See the species affected, top reactions, and outcomes below.

43
adverse-event reports
2.3%
death-coded share
Dog
most-reported species
11
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
43
Total Reports
1
Deaths Reported
2.3%
Death Rate

Active Ingredients

Topical Skin Treatment (Unknown)

Administration Routes

TopicalUnknown

Species Affected

Dog 35
Cat 8

Most Affected Breeds

Terrier - West Highland White 3
Shepherd Dog - German 3
Domestic Shorthair 3
Spaniel - Cocker American 3
Terrier - Yorkshire 3
Retriever - Labrador 2
Bulldog 2
Chihuahua 2
Cat (unknown) 2
Terrier - Bull 2

Most Reported Reactions

Vomiting 11
Lethargy (see also Central nervous system depression in 'Neurological') 6
Not eating 6
Weight loss 5
Diarrhoea 4
Other abnormal test result NOS 4
Lethargy (see also Central nervous system depression in Neurological) 4
Elevated serum alkaline phosphatase (ALP) 4
Lack of efficacy - NOS 3
Lack of efficacy (ectoparasite) - flea 3
Behavioural disorder NOS 3
Febrile 3

Outcome Breakdown

Ongoing
18 (41.9%)
Recovered/Normal
12 (27.9%)
Outcome Unknown
10 (23.3%)
Recovered with Sequela
2 (4.7%)
Died
1 (2.3%)

Topical Skin Treatment (Unknown) Adverse Event Insights

43 reports name Topical Skin Treatment (Unknown); 1 recorded a death outcome (2.3% of reported events, not a population-level mortality rate). Active ingredient: Topical Skin Treatment (Unknown). Administration routes: Topical, Unknown.

By species: Dog (35 reports), Cat (8 reports). By breed: Terrier - West Highland White (3), Shepherd Dog - German (3), Domestic Shorthair (3).

Leading clinical signs: Vomiting (11), Lethargy (see also Central nervous system depression in 'Neurological') (6), Not eating (6), Weight loss (5). Outcome, 43 coded reports: Ongoing leads at 41.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.