Drug profile

The FDA adverse-event record for Tiletamine

32 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Tiletamine. See the species affected, top reactions, and outcomes below.

32
adverse-event reports
9.4%
death-coded share
Cat
most-reported species
5
Decreased appetite - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
32
Total Reports
3
Deaths Reported
9.4%
Death Rate

Active Ingredients

Tiletamine

Administration Routes

UnknownParenteralIntravenousIntramuscularSubcutaneous

Species Affected

Cat 21
Dog 11

Most Affected Breeds

Domestic Shorthair 15
Retriever - Labrador 3
Domestic Longhair 3
Cat (unknown) 2
Shih Tzu 1
Rottweiler 1
Shepherd Dog - German 1
Mixed (Dog) 1
Shepherd Dog - Australian 1
Terrier - Boston 1

Most Reported Reactions

Decreased appetite 5
Behavioural disorder NOS 5
Vomiting 4
Hypothermia 3
Death 3
Walking difficulty 3
Not eating 3
Seizure NOS 3
Hyperactivity 3
Elevated temperature 3
Dehydration 2
Sedation prolonged 2

Outcome Breakdown

Recovered/Normal
11 (34.4%)
Ongoing
9 (28.1%)
Outcome Unknown
9 (28.1%)
Died
3 (9.4%)

Tiletamine Adverse Event Insights

32 reports name Tiletamine; 3 recorded a death outcome (9.4% of reported events, not a population-level mortality rate). Active ingredient: Tiletamine. Administration routes: Unknown, Parenteral, Intravenous, Intramuscular.

By species: Cat (21 reports), Dog (11 reports). By breed: Domestic Shorthair (15), Retriever - Labrador (3), Domestic Longhair (3).

Leading clinical signs: Decreased appetite (5), Behavioural disorder NOS (5), Vomiting (4), Hypothermia (3). Outcome, 32 coded reports: Recovered/Normal leads at 34.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.