Thyroid Supplement

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129 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
129
Total Reports
19
Deaths Reported
1470.0%
Death Rate

Active Ingredients

Thyroid Supplement

Administration Routes

OralUnknown

Species Affected

Dog 128
Cat 1

Most Affected Breeds

Retriever - Labrador 16
Retriever - Golden 12
Crossbred Canine/dog 8
Boxer (German Boxer) 7
Beagle 6
Terrier (unspecified) 5
Shepherd Dog - German 4
Dog (unknown) 4
Pug 3
Rottweiler 3

Most Reported Reactions

Weight loss 20
Diarrhoea 17
Death by euthanasia 16
Lack of efficacy - NOS 16
Vomiting 15
Lethargy (see also Central nervous system depression in 'Neurological') 13
Decreased appetite 13
Elevated alanine aminotransferase (ALT) 11
INEFFECTIVE, LOSS OF EFFECT 11
Elevated serum alkaline phosphatase (SAP) 10
Decreased urine concentration 10
Polydipsia 9

Outcome Breakdown

Ongoing
49 (38.0%)
Outcome Unknown
37 (28.7%)
Recovered/Normal
24 (18.6%)
Euthanized
16 (12.4%)
Died
3 (2.3%)

Data Summary

Metric Value
Total adverse event reports 129
Reports involving death 19
Case-fatality rate (reported events) 1470.0%
Distinct species in reports 2
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Thyroid Supplement Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 129 adverse event reports referencing Thyroid Supplement, including 19 reports in which the animal died — a 1470.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Thyroid Supplement. Reported administration routes include Oral, Unknown. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Thyroid Supplement reports are Dog (128 reports), Cat (1 reports), with Dog accounting for the largest share. Within those species, Retriever - Labrador (16), Retriever - Golden (12), Crossbred Canine/dog (8) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Thyroid Supplement are Weight loss (20), Diarrhoea (17), Death by euthanasia (16), Lack of efficacy - NOS (16). Of the 129 reports with a coded outcome, Ongoing is the leading category at 38.0%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Thyroid Supplement.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial