Drug profile

The FDA adverse-event record for Thyroid Medication (Unknown)

388 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Thyroid Medication (Unknown). See the species affected, top reactions, and outcomes below.

388
adverse-event reports
4.1%
death-coded share
Dog
most-reported species
89
Emesis - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
388
Total Reports
16
Deaths Reported
4.1%
Death Rate

Active Ingredients

Thyroid Medication (Unknown)

Administration Routes

OralUnknownAuricular (Otic)TopicalTransdermalIntraocular

Species Affected

Dog 343
Cat 32
Human 10
Unknown 3

Most Affected Breeds

Retriever - Labrador 52
Retriever - Golden 24
Crossbred Canine/dog 18
Domestic Shorthair 16
Spaniel - Cocker American 13
Unknown 13
Terrier - Yorkshire 12
Beagle 12
Chihuahua 11
Boxer (German Boxer) 9

Most Reported Reactions

Emesis 89
Vomiting 75
Lethargy (see also Central nervous system depression in 'Neurological') 42
Lack of efficacy - NOS 40
Lack of efficacy (ectoparasite) - flea 34
Diarrhoea 34
Not eating 19
Behavioural disorder NOS 17
Weight loss 16
Other abnormal test result NOS 16
Decreased appetite 15
Anorexia 14

Outcome Breakdown

Recovered/Normal
176 (45.7%)
Outcome Unknown
110 (28.6%)
Ongoing
50 (13.0%)
Recovered with Sequela
33 (8.6%)
Euthanized
12 (3.1%)
Died
4 (1.0%)

Thyroid Medication (Unknown) Adverse Event Insights

388 reports name Thyroid Medication (Unknown); 16 recorded a death outcome (4.1% of reported events, not a population-level mortality rate). Active ingredient: Thyroid Medication (Unknown). Administration routes: Oral, Unknown, Auricular (Otic), Topical.

By species: Dog (343 reports), Cat (32 reports), Human (10 reports). By breed: Retriever - Labrador (52), Retriever - Golden (24), Crossbred Canine/dog (18).

Leading clinical signs: Emesis (89), Vomiting (75), Lethargy (see also Central nervous system depression in 'Neurological') (42), Lack of efficacy - NOS (40). Outcome, 385 coded reports: Recovered/Normal leads at 45.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.