Drug profile

The FDA adverse-event record for Theophphylline

18 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Theophphylline. See the species affected, top reactions, and outcomes below.

18
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
8
Emesis - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
18
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Theophphylline

Administration Routes

UnknownOral

Species Affected

Dog 17
Cat 1

Most Affected Breeds

Spitz - German Pomeranian 4
Terrier - Jack Russell 3
Terrier - Yorkshire 1
Terrier - West Highland White 1
Dachshund (unspecified) 1
Doberman Pinscher 1
Poodle (unspecified) 1
Japanese Chin (Spaniel) 1
Domestic Shorthair 1
Shepherd Dog - Australian 1

Most Reported Reactions

Emesis 8
Vomiting 4
Diarrhoea 3
Increased heart rate 2
Elevated temperature 2
Anorexia 1
Accidental exposure 1
Lack of efficacy - NOS 1
Lack of efficacy (endoparasite) - whipworm 1
Abnormal urine odour 1
Decreased appetite 1
Lethargy (see also Central nervous system depression in 'Neurological') 1

Outcome Breakdown

Recovered/Normal
11 (61.1%)
Outcome Unknown
4 (22.2%)
Recovered with Sequela
2 (11.1%)
Ongoing
1 (5.6%)

Theophphylline Adverse Event Insights

18 reports name Theophphylline; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Theophphylline. Administration routes: Unknown, Oral.

By species: Dog (17 reports), Cat (1 reports). By breed: Spitz - German Pomeranian (4), Terrier - Jack Russell (3), Terrier - Yorkshire (1).

Leading clinical signs: Emesis (8), Vomiting (4), Diarrhoea (3), Increased heart rate (2). Outcome, 18 coded reports: Recovered/Normal leads at 61.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.