Drug profile

The FDA adverse-event record for Subcutaneous Fluids

453 FDA reports name Subcutaneous Fluids, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#326 of 2,679
by report volume (all drugs)
453
adverse-event reports
27.8%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Subcutaneous Fluids ranks #326 of 2679 by total reports (453) and #141 of 1130 by death-coded share (27.8%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#326
This drug, reports of 2679
#141
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Subcutaneous Fluids has 453 reports now versus 441 in that prior snapshot: 12 more (2.7%).

Report change
+12
Death-coded reports
+4
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Subcutaneous Fluids changes

Signature read: death-coded report count at 126 is the most distinctive stamp on Subcutaneous Fluids's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
453
Total Reports
126
Deaths Reported
27.8%
Death-coded share of reports

Active Ingredients

Subcutaneous Fluids

Administration Routes

SubcutaneousUnknownTopical

Species Affected

Cat 233
Dog 219
Rabbit 1

Most Affected Breeds

Domestic Shorthair 126
Domestic Longhair 35
Crossbred Canine/dog 21
Retriever - Labrador 17
Cat (unknown) 16
Domestic Mediumhair 15
Cat (other) 12
Terrier - Yorkshire 11
Retriever - Golden 10
Boxer (German Boxer) 10

Most Reported Reactions

Vomiting 118
Anorexia 93
Lethargy (see also Central nervous system depression in Neurological) 80
Lethargy (see also Central nervous system depression in 'Neurological') 74
Ataxia 69
Death by euthanasia 64
Diarrhoea 64
Weight loss 61
Other abnormal test result NOS 59
Death 59
Not eating 58
Fever 51

Outcome Breakdown

Ongoing
158 (34.9%)
Outcome Unknown
90 (19.9%)
Recovered/Normal
75 (16.6%)
Euthanized
64 (14.1%)
Died
62 (13.7%)
Recovered with Sequela
4 (0.9%)

Subcutaneous Fluids: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Subcutaneous Fluids, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (27.8% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Subcutaneous Fluids (#326 of 2,679 by report volume); death-coded 27.8%. PlainBreed drug row · death-coded report count stamp 126 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →