Spinosad + Milbemycin Oxime

28 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

360.0%

Death Rate

Active Ingredients

Spinosad + Milbemycin Oxime

Administration Routes

OralUnknown

Species Affected

Dog 28

Most Affected Breeds

Crossbred Canine/dog 4

Retriever - Golden 3

Retriever - Labrador 3

Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2

Shepherd Dog - Australian 2

Dog (unknown) 2

Dachshund - Miniature 1

Collie - Border 1

Brittany 1

Dachshund - Standard Long-haired 1

Most Reported Reactions

INEFFECTIVE, HEARTWORM LARVAE 14

Other abnormal test result NOS 3

Diarrhoea 2

Anorexia 2

Weight loss 2

Lack of efficacy (endoparasite) - whipworm 2

Lethargy (see also Central nervous system depression in 'Neurological') 2

Pruritus 2

Lack of efficacy (endoparasite) - tapeworm 2

Underdose 1

Drug dose omission 1

Malaise 1

Outcome Breakdown

Outcome Unknown

10 (35.7%)

Ongoing

9 (32.1%)

Recovered/Normal

8 (28.6%)

Euthanized

1 (3.6%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.