Drug profile

The FDA adverse-event record for Senvelgo Velagliflozin Oral Solution

192 FDA reports name Senvelgo Velagliflozin Oral Solution, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#547 of 2,679
by report volume (all drugs)
192
adverse-event reports
14.1%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Senvelgo Velagliflozin Oral Solution ranks #547 of 2679 by total reports (192) and #399 of 1130 by death-coded share (14.1%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#547
This drug, reports of 2679
#399
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Senvelgo Velagliflozin Oral Solution has 192 reports now versus 192 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Senvelgo Velagliflozin Oral Solution changes

Signature read: death-coded report count at 27 is the most distinctive stamp on Senvelgo Velagliflozin Oral Solution's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
192
Total Reports
27
Deaths Reported
14.1%
Death-coded share of reports

Active Ingredients

Senvelgo Velagliflozin Oral Solution

Administration Routes

OralUnknownSubcutaneous

Species Affected

Cat 192

Most Affected Breeds

Domestic Shorthair 144
Domestic Longhair 18
Domestic Mediumhair 7
Maine Coon 6
Siamese 5
Crossbred Feline/cat 3
Cat (other) 3
American Curl Shorthair 2
Unknown 1
Burmese 1

Most Reported Reactions

Ketosis 63
Weight loss 46
Lack of efficacy - NOS 43
Vomiting 36
Diarrhoea 33
Lethargy (see also Central nervous system depression in Neurological) 32
Anorexia 26
Death by euthanasia 22
Ketonuria 16
Elevated alanine aminotransferase (ALT) 13
Hypokalaemia 13
Dehydration 13

Outcome Breakdown

Outcome Unknown
124 (64.6%)
Ongoing
26 (13.5%)
Euthanized
23 (12.0%)
Recovered/Normal
13 (6.8%)
Died
4 (2.1%)
Recovered with Sequela
2 (1.0%)

Senvelgo Velagliflozin Oral Solution: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Senvelgo Velagliflozin Oral Solution, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (192 here).

Similar death-coded share

Nearest other drugs by death-coded share (14.1% here), distinct from the volume row.

What to do with this drug

  • Compare Senvelgo Velagliflozin Oral Solution's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Senvelgo Velagliflozin Oral Solution (#547 of 2,679 by report volume); death-coded 14.1%. PlainBreed drug row · death-coded report count stamp 27 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →