Drug profile

The FDA adverse-event record for Senvelgo Velagliflozin Oral Solution

164 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Senvelgo Velagliflozin Oral Solution. See the species affected, top reactions, and outcomes below.

164
adverse-event reports
14.6%
death-coded share
Cat
most-reported species
53
Ketosis - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
164
Total Reports
24
Deaths Reported
14.6%
Death Rate

Active Ingredients

Senvelgo Velagliflozin Oral Solution

Administration Routes

OralUnknownSubcutaneous

Species Affected

Cat 164

Most Affected Breeds

Domestic Shorthair 124
Domestic Longhair 14
Domestic Mediumhair 7
Maine Coon 6
Siamese 5
Crossbred Feline/cat 3
Unknown 1
Russian 1
Burmese 1
American Curl Shorthair 1

Most Reported Reactions

Ketosis 53
Lack of efficacy - NOS 39
Weight loss 38
Vomiting 31
Diarrhoea 28
Lethargy (see also Central nervous system depression in Neurological) 25
Anorexia 22
Death by euthanasia 19
Ketonuria 14
Dehydration 13
Hypokalaemia 12
Diabetic ketoacidosis 11

Outcome Breakdown

Outcome Unknown
100 (61.0%)
Ongoing
26 (15.9%)
Euthanized
20 (12.2%)
Recovered/Normal
12 (7.3%)
Died
4 (2.4%)
Recovered with Sequela
2 (1.2%)

Senvelgo Velagliflozin Oral Solution Adverse Event Insights

164 reports name Senvelgo Velagliflozin Oral Solution; 24 recorded a death outcome (14.6% of reported events, not a population-level mortality rate). Active ingredient: Senvelgo Velagliflozin Oral Solution. Administration routes: Oral, Unknown, Subcutaneous.

By species: Cat (164 reports). By breed: Domestic Shorthair (124), Domestic Longhair (14), Domestic Mediumhair (7).

Leading clinical signs: Ketosis (53), Lack of efficacy - NOS (39), Weight loss (38), Vomiting (31). Outcome, 164 coded reports: Outcome Unknown leads at 61.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.