Selamectin
30,845 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
30,845
Total Reports
1,015
Deaths Reported
330.0%
Death Rate
Active Ingredients
Selamectin
Administration Routes
TopicalUnknownOralSubcutaneousOtherOphthalmicRespiratory (Inhalation)Auricular (Otic)IntraocularCutaneous
Species Affected
Cat 13,878
Dog 12,399
Unknown 3,730
Human 709
Rabbit 66
Guinea Pig 17
Ferret 17
Other Rodents 5
Other 4
Hamster 3
Most Affected Breeds
Domestic Shorthair 6,642
Unknown 4,527
Domestic (unspecified) 1,991
Retriever - Labrador 1,206
Cat (other) 1,097
Cat (unknown) 991
Crossbred Canine/dog 934
Domestic Longhair 846
Dog (unknown) 819
Chihuahua 652
Most Reported Reactions
Lack of efficacy (ectoparasite) - flea 3,249
Application site alopecia 3,082
Vomiting 2,511
INEFFECTIVE, HEARTWORM LARVAE 2,298
Lethargy (see also Central nervous system depression in 'Neurological') 2,293
Application site hair loss 2,240
Underfilling, Tubes 1,919
Anorexia 1,478
Diarrhoea 1,248
Lack of efficacy - NOS 1,047
Behavioural disorder NOS 945
Lack of efficacy (endoparasite) - hookworm 927
Outcome Breakdown
Outcome Unknown
9,008 (40.9%)
Ongoing
8,827 (40.1%)
Recovered/Normal
3,136 (14.2%)
Died
753 (3.4%)
Euthanized
264 (1.2%)
Recovered with Sequela
23 (0.1%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.