Drug profile

The FDA adverse-event record for Sarolaner, Moxidectin, And Pyrantel

22 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Sarolaner, Moxidectin, And Pyrantel. See the species affected, top reactions, and outcomes below.

22
adverse-event reports
4.5%
death-coded share
Dog
most-reported species
5
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
22
Total Reports
1
Deaths Reported
4.5%
Death Rate

Active Ingredients

Sarolaner, Moxidectin, And Pyrantel

Administration Routes

OralUnknown

Species Affected

Dog 22

Most Affected Breeds

Dog (unknown) 3
Siberian Husky 2
Greyhound 2
Spaniel - Cocker American 2
Havanese 2
Unknown 1
Bichon Frise 1
Boxer (German Boxer) 1
Mountain Dog - Bernese 1
Terrier - Yorkshire 1

Most Reported Reactions

Vomiting 5
Scratching 4
Lack of efficacy (endoparasite) - heartworm 2
Inappetence 2
Emesis 2
Seizure NOS 2
Diarrhoea 2
Head tilt - ear disorder 2
Arrhythmia 2
Reverse sneezing 2
Horizontal nystagmus 2
Walking difficulty 2

Outcome Breakdown

Outcome Unknown
11 (50.0%)
Recovered/Normal
6 (27.3%)
Ongoing
4 (18.2%)
Euthanized
1 (4.5%)

Sarolaner, Moxidectin, And Pyrantel Adverse Event Insights

22 reports name Sarolaner, Moxidectin, And Pyrantel; 1 recorded a death outcome (4.5% of reported events, not a population-level mortality rate). Active ingredient: Sarolaner, Moxidectin, And Pyrantel. Administration routes: Oral, Unknown.

By species: Dog (22 reports). By breed: Dog (unknown) (3), Siberian Husky (2), Greyhound (2).

Leading clinical signs: Vomiting (5), Scratching (4), Lack of efficacy (endoparasite) - heartworm (2), Inappetence (2). Outcome, 22 coded reports: Outcome Unknown leads at 50.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.