S-Adenosylmethionine,Silybin,Phospholipid Supplement

36 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
36
Total Reports
7
Deaths Reported
1940.0%
Death Rate

Active Ingredients

S-Adenosylmethionine,Silybin,Phospholipid Supplement

Administration Routes

UnknownOral

Species Affected

Dog 33
Cat 3

Most Affected Breeds

Pointing Dog - Hungarian Short-haired (Vizsla) 4
Retriever - Labrador 3
Spitz - German Pomeranian 3
Dachshund (unspecified) 2
Boxer (German Boxer) 2
Terrier - Jack Russell 2
Domestic Shorthair 2
Terrier (unspecified) 1
Chinese Crested Dog – Powder Puff with veil coat 1
Poodle - Standard 1

Most Reported Reactions

Vomiting 12
Elevated alanine aminotransferase (ALT) 9
Elevated serum alkaline phosphatase (ALP) 9
Diarrhoea 7
Lethargy (see also Central nervous system depression in Neurological) 6
Elevated liver enzymes NOS 6
Death by euthanasia 5
Elevated total bilirubin 4
Other abnormal test result NOS 4
Abnormal radiograph finding 3
Liver failure 3
Unclassifiable adverse event 3

Outcome Breakdown

Recovered/Normal
13 (36.1%)
Outcome Unknown
9 (25.0%)
Ongoing
7 (19.4%)
Euthanized
5 (13.9%)
Died
2 (5.6%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.