S-Adenosylmethionine/Silybin

16 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

1250.0%

Death Rate

Active Ingredients

S-Adenosylmethionine/Silybin

Administration Routes

OralUnknown

Species Affected

Dog 14

Cat 2

Most Affected Breeds

Dachshund (unspecified) 2

Schnauzer - Miniature 2

Crossbred Canine/dog 1

Schnauzer (unspecified) 1

Retriever - Labrador 1

Terrier - West Highland White 1

Chihuahua 1

Maltese 1

Deutsche Dogge, Great Dane 1

Beagle 1

Most Reported Reactions

Other abnormal test result NOS 6

Elevated alanine aminotransferase (ALT) 3

Death by euthanasia 2

Lack of efficacy - NOS 2

Neoplasia NOS 2

Elevated serum alkaline phosphatase (SAP) 2

Acute renal failure 1

Not eating 1

Swelling NOS 1

Localised oedema (not application site) 1

Elevated creatinine 1

Elevated blood urea nitrogen (BUN) 1

Outcome Breakdown

Ongoing

6 (37.5%)

Outcome Unknown

4 (25.0%)

Recovered/Normal

3 (18.8%)

Euthanized

2 (12.5%)

Recovered with Sequela

1 (6.3%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.