S-Adenosylmethionine/ Silybin

14 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

710.0%

Death Rate

Active Ingredients

S-Adenosylmethionine/ Silybin

Administration Routes

Oral

Species Affected

Dog 13

Cat 1

Most Affected Breeds

Terrier - Yorkshire 2

Pekingese 1

Spitz - German Pomeranian 1

Crossbred Canine/dog 1

Terrier - Tibetan 1

Maltese 1

Terrier - Jack Russell 1

Shepherd Dog - Australian 1

Retriever - Labrador 1

Pug 1

Most Reported Reactions

Other abnormal test result NOS 4

Emesis 4

Elevated alanine aminotransferase (ALT) 3

Lethargy (see also Central nervous system depression in 'Neurological') 3

Elevated serum alkaline phosphatase (SAP) 3

Diarrhoea 2

Tense abdomen 2

Decreased appetite 2

Elevated liver enzymes 2

Elevated aspartate aminotransferase (AST) 2

Elevated bile acids 1

Hyperpigmentation 1

Outcome Breakdown

Ongoing

9 (64.3%)

Recovered/Normal

4 (28.6%)

Euthanized

1 (7.1%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.