S-Adenosylmethionine, Silybin

22 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

1360.0%

Death Rate

Active Ingredients

S-Adenosylmethionine, Silybin

Administration Routes

OralUnknown

Species Affected

Dog 21

Cat 1

Most Affected Breeds

Bichon Frise 2

Chihuahua 2

Crossbred Canine/dog 2

Shepherd Dog - German 2

Dog (unknown) 1

Terrier - Jack Russell 1

Retriever - Labrador 1

Dog (other) 1

Bulldog 1

Domestic Shorthair 1

Most Reported Reactions

Diarrhoea 6

Vomiting 5

Elevated alanine aminotransferase (ALT) 4

Elevated total bilirubin 4

Polyuria 3

Thrombocytosis 3

Hyperkalaemia 3

Urinary tract infection 3

Partial lack of efficacy 3

Proteinuria 3

Seizure NOS 2

Death by euthanasia 2

Outcome Breakdown

Ongoing

11 (50.0%)

Outcome Unknown

6 (27.3%)

Recovered/Normal

2 (9.1%)

Euthanized

2 (9.1%)

Died

1 (4.5%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.