Drug profile

The FDA adverse-event record for Robenacoxib

3,714 FDA reports name Robenacoxib, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#63 of 2,679
by report volume (all drugs)
3,714
adverse-event reports
14.7%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Robenacoxib ranks #63 of 2679 by total reports (3,714) and #375 of 1130 by death-coded share (14.7%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#63
This drug, reports of 2679
#375
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Robenacoxib has 3,714 reports now versus 3,586 in that prior snapshot: 128 more (3.6%).

Report change
+128
Death-coded reports
+9
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Robenacoxib changes

Signature read: death-coded report count at 545 is the most distinctive stamp on Robenacoxib's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
3,714
Total Reports
545
Deaths Reported
14.7%
Death-coded share of reports

Active Ingredients

Robenacoxib

Administration Routes

OralUnknownSubcutaneousParenteralOtherIntravenousIntramuscularTopicalIntraocularRespiratory (Inhalation)

Species Affected

Cat 3,225
Unknown 347
Dog 129
Human 7
Other Birds 2
Rabbit 2
Ferret 2

Most Affected Breeds

Domestic Shorthair 1,853
Cat (unknown) 443
Unknown 363
Domestic Longhair 226
Domestic Mediumhair 189
Siamese 83
Maine Coon 71
Domestic (unspecified) 68
Ragdoll 37
Cat (other) 35

Most Reported Reactions

Not eating 438
Lethargy (see also Central nervous system depression in 'Neurological') 369
Lack of efficacy - NOS 339
Behavioural disorder NOS 325
Death by euthanasia 304
Vomiting 302
Other abnormal test result NOS 290
Anorexia 289
Lethargy (see also Central nervous system depression in Neurological) 282
Fever 275
Weight loss 232
Death 220

Outcome Breakdown

Ongoing
1,053 (31.4%)
Outcome Unknown
940 (28.0%)
Recovered/Normal
810 (24.1%)
Died
282 (8.4%)
Euthanized
264 (7.9%)
Recovered with Sequela
9 (0.3%)

Robenacoxib: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Robenacoxib, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (14.7% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Robenacoxib (#63 of 2,679 by report volume); death-coded 14.7%. PlainBreed drug row · death-coded report count stamp 545 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →