Drug profile

The FDA adverse-event record for Robenacoxib

3,436 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Robenacoxib. See the species affected, top reactions, and outcomes below.

3,436
adverse-event reports
14.7%
death-coded share
Cat
most-reported species
378
Not eating - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
3,436
Total Reports
506
Deaths Reported
14.7%
Death Rate

Active Ingredients

Robenacoxib

Administration Routes

OralUnknownSubcutaneousParenteralIntravenousOtherIntramuscularTopicalIntraocularRespiratory (Inhalation)

Species Affected

Cat 2,962
Unknown 333
Dog 129
Human 6
Other Birds 2
Rabbit 2
Ferret 2

Most Affected Breeds

Domestic Shorthair 1,691
Cat (unknown) 423
Unknown 348
Domestic Longhair 203
Domestic Mediumhair 165
Siamese 80
Domestic (unspecified) 66
Maine Coon 66
Ragdoll 33
Cat (other) 31

Most Reported Reactions

Not eating 378
Lethargy (see also Central nervous system depression in 'Neurological') 369
Lack of efficacy - NOS 310
Behavioural disorder NOS 288
Vomiting 283
Death by euthanasia 278
Anorexia 277
Other abnormal test result NOS 270
Fever 245
Weight loss 216
Lethargy (see also Central nervous system depression in Neurological) 215
Death 207

Outcome Breakdown

Ongoing
942 (30.4%)
Outcome Unknown
880 (28.4%)
Recovered/Normal
757 (24.5%)
Died
269 (8.7%)
Euthanized
238 (7.7%)
Recovered with Sequela
8 (0.3%)

Robenacoxib Adverse Event Insights

3,436 reports name Robenacoxib; 506 recorded a death outcome (14.7% of reported events, not a population-level mortality rate). Active ingredient: Robenacoxib. Administration routes: Oral, Unknown, Subcutaneous, Parenteral.

By species: Cat (2,962 reports), Unknown (333 reports), Dog (129 reports). By breed: Domestic Shorthair (1,691), Cat (unknown) (423), Unknown (348).

Leading clinical signs: Not eating (378), Lethargy (see also Central nervous system depression in 'Neurological') (369), Lack of efficacy - NOS (310), Behavioural disorder NOS (288). Outcome, 3,094 coded reports: Ongoing leads at 30.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.