Drug profile

The FDA adverse-event record for Recombitek Lyme - 2126.R0

2,012 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Recombitek Lyme - 2126.R0. See the species affected, top reactions, and outcomes below.

2,012
adverse-event reports
1.0%
death-coded share
Dog
most-reported species
1,246
Lack of efficacy (bacteria) - Borrelia - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
2,012
Total Reports
21
Deaths Reported
1.0%
Death Rate

Active Ingredients

Recombitek Lyme - 2126.R0

Administration Routes

SubcutaneousUnknownSubconjunctivalIntramuscularDentalOral

Species Affected

Dog 2,011
Horse 1

Most Affected Breeds

Retriever - Labrador 356
Retriever - Golden 221
Shepherd Dog - German 122
Shepherd Dog - Australian 96
Crossbred Canine/dog 82
Mountain Dog - Bernese 70
Beagle 63
Collie - Border 45
Siberian Husky 38
Boxer (German Boxer) 37

Most Reported Reactions

Lack of efficacy (bacteria) - Borrelia 1,246
Lack of efficacy (ectoparasite) - tick NOS 701
Lack of efficacy (bacteria) - NOS 575
Lack of efficacy (tick) 446
Lack of efficacy (bacteria) - Anaplasma 82
Vomiting 66
Lethargy (see also Central nervous system depression in 'Neurological') 49
Diarrhoea 40
Systemic disorder NOS 35
Drug dose omission 35
Other abnormal test result NOS 34
Underdose 24

Outcome Breakdown

Outcome Unknown
1,393 (69.2%)
Ongoing
509 (25.3%)
Recovered/Normal
81 (4.0%)
Euthanized
15 (0.7%)
Recovered with Sequela
10 (0.5%)
Died
6 (0.3%)

Recombitek Lyme - 2126.R0 Adverse Event Insights

2,012 reports name Recombitek Lyme - 2126.R0; 21 recorded a death outcome (1.0% of reported events, not a population-level mortality rate). Active ingredient: Recombitek Lyme - 2126.R0. Administration routes: Subcutaneous, Unknown, Subconjunctival, Intramuscular.

By species: Dog (2,011 reports), Horse (1 reports). By breed: Retriever - Labrador (356), Retriever - Golden (221), Shepherd Dog - German (122).

Leading clinical signs: Lack of efficacy (bacteria) - Borrelia (1,246), Lack of efficacy (ectoparasite) - tick NOS (701), Lack of efficacy (bacteria) - NOS (575), Lack of efficacy (tick) (446). Outcome, 2,014 coded reports: Outcome Unknown leads at 69.2%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.