Recombinant E. Coli Bl21;Recombinant E. Coli Ecl19
2,032 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
2,032
Total Reports
34
Deaths Reported
170.0%
Death Rate
Active Ingredients
Recombinant E. Coli Bl21;Recombinant E. Coli Ecl19
Administration Routes
SubcutaneousUnknownOral
Species Affected
Dog 2,032
Most Affected Breeds
Retriever - Labrador 329
Retriever - Golden 258
Shepherd Dog - German 125
Crossbred Canine/dog 97
Shepherd Dog - Australian 77
Mountain Dog - Bernese 60
Terrier - Bull - American Pit 59
Siberian Husky 54
Shih Tzu 50
Collie - Border 39
Most Reported Reactions
Lack of efficacy (bacteria) - Borrelia 1,819
Medication error NOS 216
Lack of efficacy (ectoparasite) - tick NOS 152
Intentional misuse 150
Lack of efficacy (bacteria) - Anaplasma 113
Vomiting 64
Lethargy (see also Central nervous system depression in Neurological) 50
Facial swelling (see also Skin) 36
Hives (see also Skin) 25
Anaphylaxis 24
Not eating 23
Lack of efficacy (bacteria) - Ehrlichia 22
Outcome Breakdown
Ongoing
1,856 (91.3%)
Recovered/Normal
97 (4.8%)
Outcome Unknown
45 (2.2%)
Euthanized
22 (1.1%)
Died
12 (0.6%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.