Recombinant E. Coli Bl21;Recombinant E. Coli Ecl19
2,588 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
2,588
Total Reports
72
Deaths Reported
280.0%
Death Rate
Active Ingredients
Recombinant E. Coli Bl21;Recombinant E. Coli Ecl19
Administration Routes
SubcutaneousUnknownOralSubconjunctivalIntramuscularIntrathoracicTopicalRectal
Species Affected
Dog 2,587
Marsupial 1
Most Affected Breeds
Retriever - Labrador 383
Retriever - Golden 251
Shepherd Dog - German 152
Terrier - Bull - American Pit 109
Shepherd Dog - Australian 98
Crossbred Canine/dog 88
Siberian Husky 70
Beagle 67
Boxer (German Boxer) 57
Mountain Dog - Bernese 54
Most Reported Reactions
Lack of efficacy (bacteria) - Borrelia 1,724
Lack of efficacy (ectoparasite) - tick NOS 862
Vomiting 287
Lack of efficacy (tick) 214
Facial swelling (see also 'Skin') 154
Lethargy (see also Central nervous system depression in 'Neurological') 148
Hives (see also 'Skin') 125
Anaphylaxis 106
Lack of efficacy (bacteria) - NOS 84
Diarrhoea 81
Pale mucous membrane 62
Fever 61
Outcome Breakdown
Ongoing
2,170 (83.8%)
Recovered/Normal
299 (11.6%)
Outcome Unknown
47 (1.8%)
Euthanized
43 (1.7%)
Died
29 (1.1%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.