Drug profile

The FDA adverse-event record for Ranitidine Hcl

15 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Ranitidine Hcl. See the species affected, top reactions, and outcomes below.

15
adverse-event reports
33.3%
death-coded share
Dog
most-reported species
6
Diarrhoea - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
15
Total Reports
5
Deaths Reported
33.3%
Death Rate

Active Ingredients

Ranitidine Hcl

Administration Routes

UnknownOral

Species Affected

Dog 15

Most Affected Breeds

Retriever - Labrador 3
Retriever - Golden 1
Setter - Irish Red 1
Collie - Border 1
Spaniel (unspecified) 1
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Siberian Husky 1
Shih Tzu 1
Terrier - Boston 1
Bulldog - French 1

Most Reported Reactions

Diarrhoea 6
Vomiting 6
Anorexia 4
Anaemia NOS 3
Death 3
Neutropenia 2
Lack of efficacy - NOS 2
Blood in faeces 2
Other abnormal test result NOS 2
Elevated blood urea nitrogen (BUN) 2
Hyponatremia 2
Dehydration 2

Outcome Breakdown

Ongoing
9 (56.3%)
Died
3 (18.8%)
Recovered/Normal
2 (12.5%)
Euthanized
2 (12.5%)

Ranitidine Hcl Adverse Event Insights

15 reports name Ranitidine Hcl; 5 recorded a death outcome (33.3% of reported events, not a population-level mortality rate). Active ingredient: Ranitidine Hcl. Administration routes: Unknown, Oral.

By species: Dog (15 reports). By breed: Retriever - Labrador (3), Retriever - Golden (1), Setter - Irish Red (1).

Leading clinical signs: Diarrhoea (6), Vomiting (6), Anorexia (4), Anaemia NOS (3). Outcome, 16 coded reports: Ongoing leads at 56.3%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.