Drug profile

The FDA adverse-event record for Rabies Vaccination

62 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Rabies Vaccination. See the species affected, top reactions, and outcomes below.

62
adverse-event reports
12.9%
death-coded share
Cat
most-reported species
17
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
62
Total Reports
8
Deaths Reported
12.9%
Death Rate

Active Ingredients

Rabies Vaccination

Administration Routes

SubcutaneousUnknown

Species Affected

Cat 33
Dog 29

Most Affected Breeds

Domestic Shorthair 22
Retriever - Labrador 5
Shepherd Dog - Australian 4
Pit Bull 3
Shih Tzu 3
Persian 2
Chihuahua 2
Domestic Longhair 2
Siamese 2
Cat (unknown) 2

Most Reported Reactions

Vomiting 17
Lethargy (see also Central nervous system depression in 'Neurological') 15
Anorexia 10
Other abnormal test result NOS 9
Weight loss 9
Decreased appetite 8
Behavioural disorder NOS 7
Emesis 6
Diarrhoea 6
Ataxia 6
Application site alopecia 5
Elevated blood urea nitrogen (BUN) 5

Outcome Breakdown

Outcome Unknown
30 (48.4%)
Recovered/Normal
22 (35.5%)
Died
5 (8.1%)
Euthanized
3 (4.8%)
Ongoing
2 (3.2%)

Rabies Vaccination Adverse Event Insights

62 reports name Rabies Vaccination; 8 recorded a death outcome (12.9% of reported events, not a population-level mortality rate). Active ingredient: Rabies Vaccination. Administration routes: Subcutaneous, Unknown.

By species: Cat (33 reports), Dog (29 reports). By breed: Domestic Shorthair (22), Retriever - Labrador (5), Shepherd Dog - Australian (4).

Leading clinical signs: Vomiting (17), Lethargy (see also Central nervous system depression in 'Neurological') (15), Anorexia (10), Other abnormal test result NOS (9). Outcome, 62 coded reports: Outcome Unknown leads at 48.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.