Drug profile

The FDA adverse-event record for Rabacfosadine Succinate

341 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Rabacfosadine Succinate. See the species affected, top reactions, and outcomes below.

341
adverse-event reports
33.1%
death-coded share
Dog
most-reported species
109
Anorexia - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
341
Total Reports
113
Deaths Reported
33.1%
Death Rate

Active Ingredients

Rabacfosadine Succinate

Administration Routes

IntravenousUnknownParenteral

Species Affected

Dog 338
Cat 1
Human 1
Other Mammals 1

Most Affected Breeds

Retriever - Golden 37
Unknown 36
Retriever - Labrador 33
Boxer (German Boxer) 17
Shepherd Dog - German 16
Spaniel - Cocker American 12
Crossbred Canine/dog 11
Terrier - Bull - American Pit 10
Collie - Border 9
Poodle - Standard 8

Most Reported Reactions

Anorexia 109
Diarrhoea 99
Lethargy (see also Central nervous system depression in 'Neurological') 89
Weight loss 75
Death by euthanasia 75
Lack of efficacy - NOS 68
Elevated liver enzymes 46
Neutropenia 45
Vomiting 40
Alopecia 40
Neutrophilia 39
Thrombocytopenia 38

Outcome Breakdown

Outcome Unknown
133 (39.0%)
Euthanized
77 (22.6%)
Recovered/Normal
52 (15.2%)
Ongoing
37 (10.9%)
Died
36 (10.6%)
Recovered with Sequela
6 (1.8%)

Rabacfosadine Succinate Adverse Event Insights

341 reports name Rabacfosadine Succinate; 113 recorded a death outcome (33.1% of reported events, not a population-level mortality rate). Active ingredient: Rabacfosadine Succinate. Administration routes: Intravenous, Unknown, Parenteral.

By species: Dog (338 reports), Cat (1 reports), Human (1 reports). By breed: Retriever - Golden (37), Unknown (36), Retriever - Labrador (33).

Leading clinical signs: Anorexia (109), Diarrhoea (99), Lethargy (see also Central nervous system depression in 'Neurological') (89), Weight loss (75). Outcome, 341 coded reports: Outcome Unknown leads at 39.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.