Pyrimethamine + Sulfadiazine

23 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

1300.0%

Death Rate

Active Ingredients

PyrimethamineSulfadiazine

Administration Routes

OralUnknown

Species Affected

Horse 20

Unknown 3

Most Affected Breeds

Quarter Horse 6

Unknown 5

Thoroughbred 3

Standardbred (unspecified) 2

Mixed (Horse) 2

Pura Raza Española (Andalusian) 1

Warmblood (unspecified) 1

Missouri Fox Trotting Horse 1

Rocky Mountain Horse 1

Horse (other) 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 4

Potency, Low 3

Leucopenia NOS 3

Diarrhoea 3

Decreased appetite 3

Death by euthanasia 2

Restlessness 2

Lack of efficacy - NOS 2

Lack of efficacy (protozoa) - NOS 2

Product problem 2

Neurological signs NOS 2

Ataxia 2

Outcome Breakdown

Outcome Unknown

9 (45.0%)

Recovered/Normal

6 (30.0%)

Euthanized

2 (10.0%)

Ongoing

2 (10.0%)

Died

1 (5.0%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.