Drug profile

The FDA adverse-event record for Purevax Feline 3/Rabies - 16T9.R0

35 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Purevax Feline 3/Rabies - 16T9.R0. Species, reactions, and outcomes follow.

#1339 of 2,679
by report volume (all drugs)
35
adverse-event reports
22.9%
death-coded share
Cat
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Purevax Feline 3/Rabies - 16T9.R0 ranks #1331 of 2679 by total reports (35). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1331
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Purevax Feline 3/Rabies - 16T9.R0 has 35 reports now versus 34 in that prior snapshot: 1 more (2.9%).

Report change
+1
Death-coded reports
+1
Death-coded share
+2.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Purevax Feline 3/Rabies - 16T9.R0 changes

Signature read: Purevax Feline 3/Rabies - 16T9.R0's 22.9% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
35
Total Reports
8
Deaths Reported
22.9%
Death-coded share of reports

Active Ingredients

Purevax Feline 3/Rabies - 16T9.R0

Administration Routes

SubcutaneousUnknown

Species Affected

Cat 35

Most Affected Breeds

Domestic Shorthair 27
Domestic Longhair 3
Cat (unknown) 2
Chartreuse 1
British cat 1
Ragdoll 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in Neurological) 10
Vomiting 6
Death by euthanasia 6
Ataxia 5
Not eating 5
Behavioural disorder NOS 5
Hyperglycaemia 5
Neutrophilia 5
Fever 5
Dilated pupils 4
Diarrhoea 3
Weight loss 3

Outcome Breakdown

Recovered/Normal
13 (37.1%)
Outcome Unknown
11 (31.4%)
Euthanized
6 (17.1%)
Ongoing
3 (8.6%)
Died
2 (5.7%)

Purevax Feline 3/Rabies - 16T9.R0: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Purevax Feline 3/Rabies - 16T9.R0 (#1339 of 2,679 by report volume); death-coded 22.9%. PlainBreed drug row · death-coded share stamp 22.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →