Drug profile

The FDA adverse-event record for Prozinc Human Insulin

24 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Prozinc Human Insulin. See the species affected, top reactions, and outcomes below.

24
adverse-event reports
25.0%
death-coded share
Cat
most-reported species
15
Lack of efficacy - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
24
Total Reports
6
Deaths Reported
25.0%
Death Rate

Active Ingredients

Prozinc Human Insulin

Administration Routes

SubcutaneousUnknownOral

Species Affected

Cat 17
Dog 7

Most Affected Breeds

Domestic Shorthair 9
Domestic Longhair 4
Cat (unknown) 2
Pit Bull 1
Pug 1
Pinscher - Miniature 1
Schnauzer - Miniature 1
Maine Coon 1
Lhasa Apso 1
Terrier - Yorkshire 1

Most Reported Reactions

Lack of efficacy - NOS 15
Death by euthanasia 4
Lethargy (see also Central nervous system depression in Neurological) 3
INEFFECTIVE, GLYCEMIC CONTROL 3
Vomiting 3
Death 2
Seizure NOS 2
Hypoglycaemia 2
Diarrhoea 2
Elevated blood urea nitrogen (BUN) 2
Elevated symmetrical dimethylarginine (SDMA) 2
Anorexia 1

Outcome Breakdown

Outcome Unknown
9 (37.5%)
Ongoing
7 (29.2%)
Euthanized
4 (16.7%)
Recovered/Normal
2 (8.3%)
Died
2 (8.3%)

Prozinc Human Insulin Adverse Event Insights

24 reports name Prozinc Human Insulin; 6 recorded a death outcome (25.0% of reported events, not a population-level mortality rate). Active ingredient: Prozinc Human Insulin. Administration routes: Subcutaneous, Unknown, Oral.

By species: Cat (17 reports), Dog (7 reports). By breed: Domestic Shorthair (9), Domestic Longhair (4), Cat (unknown) (2).

Leading clinical signs: Lack of efficacy - NOS (15), Death by euthanasia (4), Lethargy (see also Central nervous system depression in Neurological) (3), INEFFECTIVE, GLYCEMIC CONTROL (3). Outcome, 24 coded reports: Outcome Unknown leads at 37.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.