Progesterone;Estradiol Benzoate
102 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
102
Total Reports
29
Deaths Reported
2840.0%
Death Rate
Active Ingredients
Progesterone;Estradiol Benzoate
Administration Routes
UnknownSubcutaneous
Species Affected
Cattle 74
Unknown 24
Human 3
Horse 1
Most Affected Breeds
Mixed (Cattle) 54
Unknown 27
Holstein-Friesian also known as Holstein 7
Aberdeen Angus 5
Crossbred Bovine/Cattle 2
Horse (unknown) 1
Gelbvieh 1
Charolais 1
Cattle (unknown) 1
Beefmaster 1
Most Reported Reactions
Death 22
INEFFECTIVE, WEIGHT INC 16
Implant, Abnormal 8
Underfilling, Container 8
Device Defective NOS 7
Tablets, Abnormal 7
Anaphylactic-type reaction 6
Increased sexual interest 6
Lack of efficacy - NOS 6
Containers, Abnormal 5
Anaphylaxis 4
Found dead 3
Outcome Breakdown
Outcome Unknown
51 (56.0%)
Died
28 (30.8%)
Recovered/Normal
8 (8.8%)
Ongoing
3 (3.3%)
Euthanized
1 (1.1%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.