Drug profile

The FDA adverse-event record for Prescription K/D Diet

34 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Prescription K/D Diet. Species, reactions, and outcomes follow.

#1361 of 2,679
by report volume (all drugs)
34
adverse-event reports
14.7%
death-coded share
Dog
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Prescription K/D Diet ranks #1344 of 2679 by total reports (34). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1344
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Prescription K/D Diet has 34 reports now versus 31 in that prior snapshot: 3 more (9.7%).

Report change
+3
Death-coded reports
+0
Death-coded share
−1.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Prescription K/D Diet changes

Signature read: death-coded share at 14.7% is the most distinctive stamp on Prescription K/D Diet's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
34
Total Reports
5
Deaths Reported
14.7%
Death-coded share of reports

Active Ingredients

Prescription K/D Diet

Administration Routes

OralUnknownOther

Species Affected

Dog 20
Cat 14

Most Affected Breeds

Domestic Shorthair 8
Crossbred Canine/dog 3
Cat (unknown) 3
Dog (unknown) 2
Retriever - Labrador 2
Chihuahua 2
Hound (unspecified) 1
Snowshoe 1
Basenji 1
Boxer (German Boxer) 1

Most Reported Reactions

Diarrhoea 7
Not eating 7
Behavioural disorder NOS 6
Lethargy (see also Central nervous system depression in Neurological) 6
Lethargy (see also Central nervous system depression in 'Neurological') 5
Vomiting 5
Dehydration 5
Emesis 4
Shaking 4
Decreased appetite 4
Lack of efficacy - NOS 3
Other abnormal test result NOS 3

Outcome Breakdown

Ongoing
15 (44.1%)
Outcome Unknown
8 (23.5%)
Recovered/Normal
5 (14.7%)
Died
3 (8.8%)
Euthanized
2 (5.9%)
Recovered with Sequela
1 (2.9%)

Prescription K/D Diet Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Prescription K/D Diet (#1361 of 2,679 by report volume); death-coded 14.7%. PlainBreed drug row · death-coded share stamp 14.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →