Drug profile

The FDA adverse-event record for Posatex

19 FDA reports name Posatex, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#1865 of 2,679
by report volume (all drugs)
19
adverse-event reports
26.3%
death-coded share
Dog
most-reported species
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Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Posatex ranks #1827 of 2679 by total reports (19). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1827
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Posatex has 19 reports now versus 19 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Posatex changes

Signature read: Posatex's 26.3% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
19
Total Reports
5
Deaths Reported
26.3%
Death-coded share of reports

Active Ingredients

Posatex

Administration Routes

Auricular (Otic)UnknownTopical

Species Affected

Dog 19

Most Affected Breeds

Retriever - Labrador 4
Pug 3
Shih Tzu 2
Chihuahua 2
Weimaraner 2
Crossbred Canine/dog 1
Poodle - Standard 1
Deutsche Dogge, Great Dane 1
Spaniel - Springer (unspecified) 1
Coonhound (unspecified) 1

Most Reported Reactions

Unusual stool colour 3
Death by euthanasia 3
Inappropriate urination 3
Inappropriate defecation 3
Elevated alanine aminotransferase (ALT) 2
Abnormal breathing 2
Cough 2
Death 2
Ear pruritus 2
Pinnal haemorrhage 2
Thrombocytopenia 2
Blood in faeces 2

Outcome Breakdown

Ongoing
11 (57.9%)
Euthanized
3 (15.8%)
Recovered/Normal
2 (10.5%)
Died
2 (10.5%)
Outcome Unknown
1 (5.3%)

Posatex: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Posatex (#1865 of 2,679 by report volume); death-coded 26.3%. PlainBreed drug row · death-coded share stamp 26.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →