Drug profile

The FDA adverse-event record for Pirlimycin Hydrochloride

39 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Pirlimycin Hydrochloride. See the species affected, top reactions, and outcomes below.

39
adverse-event reports
17.9%
death-coded share
Cattle
most-reported species
6
Lack of efficacy (bacteria) - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
39
Total Reports
7
Deaths Reported
17.9%
Death Rate

Active Ingredients

Pirlimycin Hydrochloride

Administration Routes

UnknownIntramammaryOphthalmic

Species Affected

Cattle 23
Unknown 12
Goat 3
Human 1

Most Affected Breeds

Unknown 13
Cattle (other) 12
Holstein-Friesian also known as Holstein 8
Jersey 3
Goat (unknown) 1
Boer 1
Nubian 1

Most Reported Reactions

Lack of efficacy (bacteria) - NOS 6
Acute mastitis 6
Death 5
Residues in milk 4
CULTURE/TITER DATA ABNORMAL 3
Lack of efficacy - NOS 3
INEFFECTIVE, ANTIBIOTIC 3
Product syringe issue 2
Solution, Abnormal 2
Containers, Leaking 2
No sign 2
Sternoabdominal recumbency 2

Outcome Breakdown

Outcome Unknown
23 (67.6%)
Died
7 (20.6%)
Recovered/Normal
3 (8.8%)
Euthanized
1 (2.9%)

Pirlimycin Hydrochloride Adverse Event Insights

39 reports name Pirlimycin Hydrochloride; 7 recorded a death outcome (17.9% of reported events, not a population-level mortality rate). Active ingredient: Pirlimycin Hydrochloride. Administration routes: Unknown, Intramammary, Ophthalmic.

By species: Cattle (23 reports), Unknown (12 reports), Goat (3 reports). By breed: Unknown (13), Cattle (other) (12), Holstein-Friesian also known as Holstein (8).

Leading clinical signs: Lack of efficacy (bacteria) - NOS (6), Acute mastitis (6), Death (5), Residues in milk (4). Outcome, 34 coded reports: Outcome Unknown leads at 67.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.