Drug profile

The FDA adverse-event record for Pergolide

19 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Pergolide. See the species affected, top reactions, and outcomes below.

19
adverse-event reports
10.5%
death-coded share
Horse
most-reported species
2
Injection site swelling - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
19
Total Reports
2
Deaths Reported
10.5%
Death Rate

Active Ingredients

Pergolide

Administration Routes

UnknownOral

Species Affected

Horse 19

Most Affected Breeds

Horse (unknown) 3
Warmblood (unspecified) 2
Paint 2
Hanovarian 2
Thoroughbred 2
Morgan 1
Quarter Horse 1
Miniature 1
Horse (other) 1
Tennessee Walking Horse 1

Most Reported Reactions

Injection site swelling 2
Injection site reaction NOS 2
Anorexia 2
Illness NOS 2
Nystagmus 2
Lack of efficacy - NOS 2
Injection site hair change 2
Uncoded sign 1
Polyuria 1
Polydipsia 1
Depression 1
Elevated creatinine 1

Outcome Breakdown

Recovered/Normal
9 (47.4%)
Outcome Unknown
8 (42.1%)
Euthanized
1 (5.3%)
Died
1 (5.3%)

Pergolide Adverse Event Insights

19 reports name Pergolide; 2 recorded a death outcome (10.5% of reported events, not a population-level mortality rate). Active ingredient: Pergolide. Administration routes: Unknown, Oral.

By species: Horse (19 reports). By breed: Horse (unknown) (3), Warmblood (unspecified) (2), Paint (2).

Leading clinical signs: Injection site swelling (2), Injection site reaction NOS (2), Anorexia (2), Illness NOS (2). Outcome, 19 coded reports: Recovered/Normal leads at 47.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.