Pentobarbital Sodium + Phenytoin Sodium
288 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
288
Total Reports
228
Deaths Reported
7920.0%
Death Rate
Active Ingredients
Pentobarbital SodiumPentobarbital Sodium + Phenytoin SodiumPhenytoin Sodium
Administration Routes
IntravenousUnknownSubcutaneousTopicalIntracardiacOphthalmicOralParenteralIntraperitonealOther
Species Affected
Dog 159
Cat 40
Unknown 37
Horse 31
Human 10
Other 4
Goat 2
Other Mammals 1
Pig 1
Chicken 1
Most Affected Breeds
Unknown 87
Dog (unknown) 31
Domestic Shorthair 19
Cat (unknown) 14
Retriever - Labrador 11
Chihuahua 10
Horse (unknown) 9
Mixed (Dog) 8
Pit Bull 6
Rottweiler 5
Most Reported Reactions
INEFFECTIVE, EUTHANASIA 137
Lack of efficacy - NOS 81
INEFFECTIVE, DELAYED EFFECT 34
Overdose 18
Death by euthanasia 17
Vocalisation 15
Agonal breathing 12
Appearance, Abnormal 11
Product Defect, General 9
Stopper, abnormal 9
Partial lack of efficacy 8
Drug administration error 8
Outcome Breakdown
Euthanized
224 (89.2%)
Recovered/Normal
17 (6.8%)
Outcome Unknown
6 (2.4%)
Died
4 (1.6%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.