Drug profile

The FDA adverse-event record for Oxytetracycline Hydrochloride

Name: Oxytetracycline Hydrochloride - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

39 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Oxytetracycline Hydrochloride. See the species affected, top reactions, and outcomes below.

39
adverse-event reports: 7.7%
death-coded share: Unknown
most-reported species: 7
Solution, Abnormal - top reaction

Compiled by PlainBreed Editorial, Pet Health Editorial Team

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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

7.7%

Death Rate

Active Ingredients

Oxytetracycline Hydrochloride

Administration Routes

UnknownOralSubcutaneousOphthalmicRespiratory (Inhalation)

Species Affected

Unknown 22

Cattle 9

Human 3

Horse 2

Sheep 1

Dog 1

Cat 1

Most Affected Breeds

Unknown 26

Crossbred Bovine/Cattle 2

Crossbred Ovine/sheep 1

Holstein-Friesian also known as Holstein 1

Cattle (unknown) 1

Limousin 1

Spaniel (unspecified) 1

Aberdeen Angus 1

Jersey 1

Cattle (other) 1

Most Reported Reactions

Solution, Abnormal 7

Color, Abnormal 5

Product Defect, General 4

Lack of efficacy (bacteria) - NOS 3

Death 3

Recumbency 3

Unclassifiable adverse event 3

Accidental exposure 3

Granules/Powder, Abnormal 3

Blindness 2

Difficulty of Use 2

Potency, Low 2

Outcome Breakdown

Recovered/Normal

6 (46.2%)

Died

3 (23.1%)

Outcome Unknown

3 (23.1%)

Ongoing

1 (7.7%)

Oxytetracycline Hydrochloride Adverse Event Insights

39 reports name Oxytetracycline Hydrochloride; 3 recorded a death outcome (7.7% of reported events, not a population-level mortality rate). Active ingredient: Oxytetracycline Hydrochloride. Administration routes: Unknown, Oral, Subcutaneous, Ophthalmic.

By species: Unknown (22 reports), Cattle (9 reports), Human (3 reports). By breed: Unknown (26), Crossbred Bovine/Cattle (2), Crossbred Ovine/sheep (1).

Leading clinical signs: Solution, Abnormal (7), Color, Abnormal (5), Product Defect, General (4), Lack of efficacy (bacteria) - NOS (3). Outcome, 13 coded reports: Recovered/Normal leads at 46.2%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.