Drug profile

The FDA adverse-event record for Orbifloxacin Tablets

33 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Orbifloxacin Tablets. See the species affected, top reactions, and outcomes below.

33
adverse-event reports
21.2%
death-coded share
Dog
most-reported species
9
Lot # and /or Expiration date missing - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
33
Total Reports
7
Deaths Reported
21.2%
Death Rate

Active Ingredients

Orbifloxacin Tablets

Administration Routes

OralUnknown

Species Affected

Dog 13
Unknown 12
Cat 8

Most Affected Breeds

Unknown 12
Domestic Shorthair 6
Crossbred Canine/dog 3
Pit Bull 2
Cat (unknown) 1
Shih Tzu 1
Russian 1
Pug 1
Chihuahua 1
Dog (unknown) 1

Most Reported Reactions

Lot # and /or Expiration date missing 9
Lethargy (see also Central nervous system depression in 'Neurological') 6
Product problem 4
Death by euthanasia 4
Seizure NOS 3
Dilated pupils 3
Elevated serum alkaline phosphatase (SAP) 3
Tablets, Abnormal 3
Blindness 3
Product label issues 3
Leucocytosis NOS 2
Anorexia 2

Outcome Breakdown

Ongoing
6 (28.6%)
Euthanized
5 (23.8%)
Outcome Unknown
3 (14.3%)
Recovered with Sequela
3 (14.3%)
Died
2 (9.5%)
Recovered/Normal
2 (9.5%)

Orbifloxacin Tablets Adverse Event Insights

33 reports name Orbifloxacin Tablets; 7 recorded a death outcome (21.2% of reported events, not a population-level mortality rate). Active ingredient: Orbifloxacin Tablets. Administration routes: Oral, Unknown.

By species: Dog (13 reports), Unknown (12 reports), Cat (8 reports). By breed: Unknown (12), Domestic Shorthair (6), Crossbred Canine/dog (3).

Leading clinical signs: Lot # and /or Expiration date missing (9), Lethargy (see also Central nervous system depression in 'Neurological') (6), Product problem (4), Death by euthanasia (4). Outcome, 21 coded reports: Ongoing leads at 28.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.