Nystatin-Neomycin Sulfate-Thiostrepton-Triamcinolone Acetonide Ointment

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43 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
43
Total Reports
6
Deaths Reported
1400.0%
Death Rate

Active Ingredients

Nystatin-Neomycin Sulfate-Thiostrepton-Triamcinolone Acetonide Ointment

Administration Routes

UnknownAuricular (Otic)Topical

Species Affected

Dog 35
Cat 8

Most Affected Breeds

Domestic Shorthair 6
Retriever - Labrador 6
Shiba Inu 4
Spaniel - Cocker American 2
Bulldog - French 2
Dog (other) 2
Dog (unknown) 2
Terrier - Irish Soft-coated Wheaten 1
Retriever - Golden 1
Lhasa Apso 1

Most Reported Reactions

Vomiting 12
Lethargy (see also Central nervous system depression in 'Neurological') 10
Lack of efficacy - NOS 4
Other abnormal test result NOS 4
Seizure NOS 4
Ear discharge 4
Decreased appetite 4
Dehydration 3
Death by euthanasia 3
Behavioural disorder NOS 3
Other ear disorder NOS 3
Depression 3

Outcome Breakdown

Ongoing
17 (39.5%)
Outcome Unknown
12 (27.9%)
Recovered/Normal
8 (18.6%)
Died
3 (7.0%)
Euthanized
3 (7.0%)

Data Summary

Metric Value
Total adverse event reports 43
Reports involving death 6
Case-fatality rate (reported events) 1400.0%
Distinct species in reports 2
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Nystatin-Neomycin Sulfate-Thiostrepton-Triamcinolone Acetonide Ointment Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 43 adverse event reports referencing Nystatin-Neomycin Sulfate-Thiostrepton-Triamcinolone Acetonide Ointment, including 6 reports in which the animal died — a 1400.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Nystatin-Neomycin Sulfate-Thiostrepton-Triamcinolone Acetonide Ointment. Reported administration routes include Unknown, Auricular (Otic), Topical. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Nystatin-Neomycin Sulfate-Thiostrepton-Triamcinolone Acetonide Ointment reports are Dog (35 reports), Cat (8 reports), with Dog accounting for the largest share. Within those species, Domestic Shorthair (6), Retriever - Labrador (6), Shiba Inu (4) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Nystatin-Neomycin Sulfate-Thiostrepton-Triamcinolone Acetonide Ointment are Vomiting (12), Lethargy (see also Central nervous system depression in 'Neurological') (10), Lack of efficacy - NOS (4), Other abnormal test result NOS (4). Of the 43 reports with a coded outcome, Ongoing is the leading category at 39.5%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Nystatin-Neomycin Sulfate-Thiostrepton-Triamcinolone Acetonide Ointment.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial