Drug profile

The FDA adverse-event record for Nystatin, Neomycin Sulfate, Thiostrepton, Triamcinolone Acetonide

35 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Nystatin, Neomycin Sulfate, Thiostrepton, Triamcinolone Acetonide. Species, reactions, and outcomes follow.

#1338 of 2,679
by report volume (all drugs)
35
adverse-event reports
11.4%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Nystatin, Neomycin Sulfate, Thiostrepton, Triamcinolone Acetonide ranks #1331 of 2679 by total reports (35). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1331
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Nystatin, Neomycin Sulfate, Thiostrepton, Triamcinolone Acetonide has 35 reports now versus 32 in that prior snapshot: 3 more (9.4%).

Report change
+3
Death-coded reports
+0
Death-coded share
−1.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Nystatin, Neomycin Sulfate, Thiostrepton, Triamcinolone Acetonide changes

Signature read: death-coded share at 11.4% is the most distinctive stamp on Nystatin, Neomycin Sulfate, Thiostrepton, Triamcinolone Acetonide's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
35
Total Reports
4
Deaths Reported
11.4%
Death-coded share of reports

Active Ingredients

Nystatin, Neomycin Sulfate, Thiostrepton, Triamcinolone Acetonide

Administration Routes

TopicalUnknownAuricular (Otic)Oral

Species Affected

Dog 30
Cat 5

Most Affected Breeds

Domestic Shorthair 4
Retriever - Labrador 3
Crossbred Canine/dog 2
Shepherd Dog - German 2
Pinscher - Miniature 2
Terrier - Jack Russell 2
Unknown 2
Bulldog 1
Deutsche Dogge, Great Dane 1
Alaskan Malamute 1

Most Reported Reactions

Vomiting 6
Lack of efficacy - NOS 6
Diarrhoea 5
Pain NOS 5
Not eating 4
Lethargy (see also Central nervous system depression in 'Neurological') 3
Death 3
Skin disorders NOS 3
Abnormal cytology 3
Ataxia 3
Skin lesion NOS 2
Decreased appetite 2

Outcome Breakdown

Ongoing
23 (65.7%)
Recovered/Normal
5 (14.3%)
Died
3 (8.6%)
Outcome Unknown
3 (8.6%)
Euthanized
1 (2.9%)

Nystatin, Neomycin Sulfate, Thiostrepton, Triamcinolone Acetonide Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Nystatin, Neomycin Sulfate, Thiostrepton, Triamcinolone Acetonide (#1338 of 2,679 by report volume); death-coded 11.4%. PlainBreed drug row · death-coded share stamp 11.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →