Drug profile

The FDA adverse-event record for Nutritional Supplement

79 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Nutritional Supplement. See the species affected, top reactions, and outcomes below.

79
adverse-event reports
17.7%
death-coded share
Dog
most-reported species
17
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
79
Total Reports
14
Deaths Reported
17.7%
Death Rate

Active Ingredients

Nutritional Supplement

Administration Routes

OralUnknown

Species Affected

Dog 68
Cat 9
Horse 2

Most Affected Breeds

Retriever - Labrador 9
Domestic Shorthair 8
Retriever - Golden 8
Crossbred Canine/dog 5
Dog (unknown) 5
Collie - Border 4
Shepherd Dog - German 3
Sheepdog - Shetland 3
Corgi - Welsh Pembroke 2
Corgi (unspecified) 2

Most Reported Reactions

Vomiting 17
Lethargy (see also Central nervous system depression in 'Neurological') 15
Diarrhoea 14
Anorexia 10
Elevated liver enzymes 9
Not eating 9
Death 9
Other abnormal test result NOS 8
Weight loss 8
Emesis 7
Elevated creatinine 7
Behavioural disorder NOS 5

Outcome Breakdown

Outcome Unknown
28 (35.4%)
Ongoing
24 (30.4%)
Recovered/Normal
12 (15.2%)
Died
9 (11.4%)
Euthanized
5 (6.3%)
Recovered with Sequela
1 (1.3%)

Nutritional Supplement Adverse Event Insights

79 reports name Nutritional Supplement; 14 recorded a death outcome (17.7% of reported events, not a population-level mortality rate). Active ingredient: Nutritional Supplement. Administration routes: Oral, Unknown.

By species: Dog (68 reports), Cat (9 reports), Horse (2 reports). By breed: Retriever - Labrador (9), Domestic Shorthair (8), Retriever - Golden (8).

Leading clinical signs: Vomiting (17), Lethargy (see also Central nervous system depression in 'Neurological') (15), Diarrhoea (14), Anorexia (10). Outcome, 79 coded reports: Outcome Unknown leads at 35.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.