Drug profile

The FDA adverse-event record for Nsaid (Unknown)

45 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Nsaid (Unknown). Species, reactions, and outcomes follow.

#1192 of 2,679
by report volume (all drugs)
45
adverse-event reports
13.3%
death-coded share
Dog
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Nsaid (Unknown) ranks #1182 of 2679 by total reports (45). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1182
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Nsaid (Unknown) has 45 reports now versus 45 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Nsaid (Unknown) changes

Signature read: death-coded share at 13.3% is the most distinctive stamp on Nsaid (Unknown)'s FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
45
Total Reports
6
Deaths Reported
13.3%
Death-coded share of reports

Active Ingredients

Nsaid (Unknown)

Administration Routes

UnknownOralIntravenous

Species Affected

Dog 43
Human 1
Cat 1

Most Affected Breeds

Retriever - Labrador 7
Crossbred Canine/dog 5
Dog (unknown) 3
Pug 2
Beagle 2
Retriever - Golden 2
Shepherd Dog - German 2
Maltese 2
Terrier - Bull - American Pit 1
Dog (other) 1

Most Reported Reactions

Vomiting 11
Emesis 6
Diarrhoea 5
Other abnormal test result NOS 5
Not eating 5
Behavioural disorder NOS 4
Death by euthanasia 4
Abnormal ultrasound finding 4
Urinary incontinence 4
Lack of efficacy - NOS 4
Lethargy (see also Central nervous system depression in 'Neurological') 3
Hyperactivity 3

Outcome Breakdown

Recovered/Normal
17 (37.8%)
Outcome Unknown
11 (24.4%)
Ongoing
7 (15.6%)
Recovered with Sequela
4 (8.9%)
Euthanized
4 (8.9%)
Died
2 (4.4%)

Nsaid (Unknown) Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Nsaid (Unknown) (#1192 of 2,679 by report volume); death-coded 13.3%. PlainBreed drug row · death-coded share stamp 13.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →