Drug profile

The FDA adverse-event record for Novox

48 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Novox. See the species affected, top reactions, and outcomes below.

48
adverse-event reports
31.3%
death-coded share
Dog
most-reported species
9
Death by euthanasia - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
48
Total Reports
15
Deaths Reported
31.3%
Death Rate

Active Ingredients

Novox

Administration Routes

OralUnknown

Species Affected

Dog 48

Most Affected Breeds

Shepherd Dog - German 7
Retriever - Golden 6
Retriever - Labrador 5
Terrier - Bull - American Pit 4
Boxer (German Boxer) 3
Crossbred Canine/dog 3
Newfoundland 2
Setter - English 1
Beagle 1
Schnauzer - Miniature 1

Most Reported Reactions

Death by euthanasia 9
Vomiting 8
Not eating 7
Partial lack of efficacy 7
Death 6
Limb weakness 6
Lethargy (see also Central nervous system depression in Neurological) 6
Polyuria 5
Polydipsia 5
Lethargy (see also Central nervous system depression in 'Neurological') 4
Fever 4
Urinary incontinence 4

Outcome Breakdown

Ongoing
22 (45.8%)
Euthanized
9 (18.8%)
Recovered/Normal
6 (12.5%)
Died
6 (12.5%)
Outcome Unknown
5 (10.4%)

Novox Adverse Event Insights

48 reports name Novox; 15 recorded a death outcome (31.3% of reported events, not a population-level mortality rate). Active ingredient: Novox. Administration routes: Oral, Unknown.

By species: Dog (48 reports). By breed: Shepherd Dog - German (7), Retriever - Golden (6), Retriever - Labrador (5).

Leading clinical signs: Death by euthanasia (9), Vomiting (8), Not eating (7), Partial lack of efficacy (7). Outcome, 48 coded reports: Ongoing leads at 45.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.